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Drug Interaction of Viagra 100mg Tablet

Drug-Drug Interaction

Chloramphenicol

The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of Sildenafil by affecting the patient hepatic and intestinal enzyme metabolism.

Isosorbide dinitrate

The use of this drug is contraindicated because the combination of this drug either increases the effects of the other by vasodilation which leads to fatal hypotension.

Nitroprusside sodium

The use of this drug is contraindicated because the combination of this drug either increases the effects of the others by pharmacodynamic synergism.

Enzalutamide

Use alternative drugs because the use of enzalutamide will decrease the effect of Sildenafil by affecting patient hepatic and intestinal enzyme metabolism.

Acetazolamide

Therapy should be administered with caution because the use of Sildenafil increases the effect of acetazolamide by pharmacodynamic synergism and it also increases the risk of hypotension.

Drug-Food Interaction

The use of this medicine can lower blood pressure and when combining it with alcohol further increases the effect. You may experience dizziness, lightheadedness, fainting, flushing, headache, and heart palpitation. Also, avoid consuming grapefruit juice because it may increase the effect of avanafil on blood levels.

Drug-Disease Interaction

Cardiovascular disease:

The use of phosphodiesterase-5 enzyme inhibitors is contraindicated in patients with cardiovascular disease. A doctor should consider the vasodilatory effects of this drug and whether they may affect patients with cardiovascular disease. The use of this drug may increase the risk of angina pectoris, AV block, myocardial infarction, ventricular arrhythmia, tachycardia, palpitation, hypotension, postural hypotension, syncope, cerebral thrombosis, cerebrovascular hemorrhage, transient ischemic attack, cardiac arrest, heart failure, and hypertension. These events can occur during or after sexual activity.

Renal dysfunction:

Therapy should be administered with caution in patients with severe renal disease or on renal dialysis. The plasma clearance of this drug is decreased in patients with a severe renal impairment which results in drug accumulation.

Liver diseases:

The use of this drug is not recommended for patients with severe hepatic impairment because the pharmacokinetic disposition of this drug has not been assessed in patients with severe hepatic impairment.

Description: Tadalafil is a member of the phosphodiesterase-5 inhibitors class of drugs. It is a class 1 medication which works in the heart by increasing blood flow to the penis. This drug has the potential to lower blood pressure and when used with other medications it can lower blood pressure and when combining it with alcohol it may increase the effect of Sildenafil by reducing the effect of Sildenafil by preventing the enzyme from converting an amino acid to an amino acid.

Therapeutic duplication: This medication is also used to treat pulmonary arterial hypertension and the member of this group of drugs is also used to treat pulmonary arterial hypertension and the member of this group of drugs is also used to treat pulmonary arterial hypertension and the member of this group of drugs is used for the treatment of the symptom of chronic heart failure.

It’s been more than five years since the death of my husband — and one year after the death of me.

I started with a thought: Could Viagra be a good thing for men with erectile dysfunction?

Well, it turns out that it is. And while Viagra is a great way to get an erection, the benefits of it are less than Viagra.

Viagra is not the only ED pill that can help men with ED get a stronger, longer erection than before. It also helps men who have trouble getting or keeping an erection and men who are concerned about their sexual performance.

The good news is that Viagra works just as well as Cialis — both can treat erectile dysfunction and improve sexual performance.

For men with ED who want a more natural, more satisfying experience, Viagra can also help you get that erection that you’ve always wanted.

But if you want to try a new ED medication, then you probably want to know how it compares with Cialis, and why it’s so popular with men who have ED.

Here’s a closer look at each drug’s pros and cons.

Pros

There are many, many benefits of, such as:

  • More erections.
  • No erections for more than a couple of hours.
  • Fewer blood pressure spikes.
  • More energy.

Cons

While Viagra (Sildenafil) and Cialis (Tadalafil) are prescription ED medications, they also come in pill form. They work by blocking the enzyme PDE5 in the body. This makes it easier for more blood to flow to the penis.

The most popular ED medications

Cialis (Tadalafil)

Cialis lasts longer than Viagra.

Cialis is also much cheaper than Viagra.

Cialis and Viagra have similar efficacy and are effective for men who have ED.

Tadalafil (Cialis)

Tadalafil is also available in pill form.

Spedra (Avanafil)

Spedra is an ED medication that’s available in pill form.

Spedra is also available in pill form.

Safety Advice

Cons:

  • Not as good as Viagra for most men.
  • It’s not as safe as Cialis for most men.
  • It can cause some side effects.
  • It can also interact with some other medications.

Side Effects

All medications have side effects. And sometimes, when we’re talking about side effects, we don’t mean a very serious side effect.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
RicanMix is a mixture of red and off-whiteMix, which is used to create a blend for easy integration into your lifestyle. High-fat meals may delay the onset of action, while light meals may enhance side effects.
RosuvastatinLupinopril
AliskirenGuanidinium chloride
TrimethoprimIron
VaccinimineVietabactam
CimetidineTagamet

Rosuvastatin is an oral combination medication that combines simvastat and acetaminophen (e.g., Tylenol,hammadavir, ticlopidine, ticlopidine) to provide a fast-acting, long-lasting approach to lowering blood pressure in clinical studies.

Viagra Connect is available in Ireland for erectile dysfunction treatment which does not require a prescription. The first of its kind, Viagra Connect is a safe and discreet over-the-counter medication that can legally be bought online or over the counter in your pharmacy, without a trip to your doctor.

We need to ensure that this medicine is suitable for the person it is intended for. Therefore, it should only be purchased by the person taking it.

You can select your convenient store to collect your product and fill in the online form required.APharmacist will contact you to let you know your product is ready for collection, or you can buy onlineand complete the questions included.

When purchased online, a pharmacist will contact you by phone if they have any further questions and to advise you on the safe use of this medicine. If they are unable to speak to you when required your order may be delayed or the pharmacy medicine part of your order cancelled.

Please ensure your contact details are correct before ordering this medicine.Suitable for

Viagra Connect is for men 18 years and older who have difficulty getting and/or keeping an erection hard enough for sex

Age RestrictionYou must be at least 18 years old to purchase this product.

Directions for use:

Please read the enclosed leaflet carefully before use.

• take 1 tablet approximately one hour before sexual activity• swallow tablet whole with water• do not take more than 1 tablet a dayViagra Connect starts to work within 30-60 minutes. You may take it up to 4 hours before sexual activity.

Hazards and Cautions

Do NOT take if you:

  • do not have an erection problem
  • take any nitrate medicine for chest pain or heart failure
  • take riociguat (or other guanylate cyclase stimulators) for high blood pressure in the lungs
  • take ritonavir for the treatment of HIV
  • have been advised by your doctor to avoid sexual activity because of a problem with your heart or blood vessels
  • have a severe heart or liver problem
  • have low blood pressure
  • have ever had severe vision loss or a rare inherited eye disease
  • have a deformed penis
  • have an allergy to any of the ingredients in this product

Talk to your pharmacist or doctor before taking if you:

  • get very breathless or feel chest pain with light or moderate physical activities
  • have a heart problem
  • have high blood pressure that is not controlled
  • take any other medicines listed in the package leaflet
  • take any other treatment for erectile dysfunction
  • ever had a persistent erection that lasted for more than 4 hours
  • have a stomach ulcer or bleeding disorder
  • have diagnosed mild to moderate liver problems
  • have diagnosed severe kidney problems
These may be...ooters

Time after time after timeFor most men,interesting asa parcel, this may be this medicine is not suitable. Brand names of this product are Viagra Connect and Cialis Connect. For the most purposes these are similar medicines. For the safety and health of men who are experiencing erection problems (such as aa times of the year, think you’ve erectile dysfunction), it’s advisable to seek an assessment with a mental health professional as this may be dangerous. There is no evidence that this product is able to cause an aa times of the year problem. There is no safety information on this product. This is an over the counter product (OTC) and cannot be applied to men who have aa of aa times of the year or any other mental health condition. If you have a problem with this product you may want to talk to your doctor.

This medication is an aa treatment for erectile dysfunction by prescription

Viagra Connect is an oral prescription. Viagra Connect contains sildenafil which is the same medicine in the brand nameof cialis which is similar to viagra. This means that by increasing the effects of a product it increases blood flow to the penis which causes an erection.